Nitrofurantoin
[CAS 67-20-9]

Identification

• Classification: API >> Synthetic anti-infective drugs >> Nitrofuran
• Name: Nitrofurantoin
• Synonyms: 1-[(5-Nitrofurfurylidene)amino]hydantoin; 1-(((5-Nitro-2-furanyl)methylene)amino)-2,4-imidazolidinedione
• Molecular Formula: C₈H₆N₄O₅
• Molecular Weight: 238.16
• CAS Registry Number: 67-20-9
• EC Number: 200-646-5

Properties

• Melting point: 268 °C
• Water solubility: <0.01 g/100 mL at 19 °C

Safety Data

• Hazard Symbols: Xn
• Risk Statements: R22;R42/43
• Safety Statements: S22;S36/37;S45

Hazard Classification

Hazard	Class	Category Code	Hazard Statement
Acute toxicity	Acute Tox.	4	H302
Respiratory sensitization	Resp. Sens.	1	H334
Skin sensitization	Skin Sens.	1	H317
Reproductive toxicity	Repr.	2	H361
Carcinogenicity	Carc.	2	H351
Chronic hazardous to the aquatic environment	Aquatic Chronic	3	H412
Specific target organ toxicity - repeated exposure	STOT RE	2	H373
Germ cell mutagenicity	Muta.	2	H341
Germ cell mutagenicity	Muta.	1B	H340
Acute toxicity	Acute Tox.	4	H332
Acute toxicity	Acute Tox.	3	H301
Acute toxicity	Acute Tox.	4	H312